concepts in drug metabolism

Lectures in Drug Metabolism For third year students; Faculty of Pharmacy; Cairo University. Published By Dr. Hanaa Hashem. Department of Pharmaceutical Chemistry

Friday, June 13, 2008

Things to remember when applying to drugs

Phase I * Cytochrome P450 looks for sites most electron rich and least sterically hindered. So aromatic rings with electron withdrawing grou...

Points to remember

1-Metabolism is a Detoxification process .........( with exceptions ) 2-Phase I Changes the structure by adding a functional group in order...

Friday, April 25, 2008

Things to remember when applying to drugs

Phase I *Cytochrome P450 looks for sites most electron rich and least sterically hindered So aromatic rings with electron withdrawing groups...

Thursday, April 10, 2008

Summary of Lecture I

DRUG METABOLISM S tructural changes that occur to a foreign molecule ( xenobiotic ) in the body D rugs should have certain lipid solubility...

Summary of Lecture II

7-Oxidation involving carbon-heteroatom systems: N itrogen, oxygen & sulfer. T wo types of biotransformation reaction 1-Hydroxylation of...

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